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Topic outline

 

  • Time: 20 hours
    Level: Advanced

 
 

Introduction

  • Introduction Resource
  • This unit examines how self-assembled structures based on lipids and proteins provide a framework for cellular processes.
 

1 Biological materials

  • 1 Biological materials Resource
  • Materials engineers have long recognised the impressive range and combination of properties offered by biological materials. Figure 1 shows some representative examples of the combination of tensile strength...
 

2 Construction with lipids

  • 2 Construction with lipids Resource
  • The cell membrane is constructed from lipids. Chemically, lipids are a rather varied group of compounds that include all the substances you might already think of as fats or oils. What they have in common...
 

3 Providing a framework: structural proteins

  • 3.1 Protein diversity Resource
  • Of course, our bodies can't just be made up of squidgy bubbles of phospholipid, or we would collapse in a heap on the floor! Stiffer frameworks, both inside and outside the cells, also exist and help to...
  • 3.2 Protein structure Resource
  • Proteins are one example of a biopolymer. You will already be familiar with synthetic polymers such as polyethylene and nylon: long chains made up of many thousands of repeating units, called monomers,...
  • 3.3 Spider silk Resource
  • The presence of regions of helical and sheet-like structures within a protein will affect its properties in different ways: a particularly striking example of this is provided by spider silk.
 

4 Engineering with proteins

  • 4 Engineering with proteins Resource
  • What are the prospects for designing and making new proteins for specific purposes? The technology exists to build polypeptide chains unit by unit in a test tube, but this is time-consuming and expensive....
 

References and Acknowledgements

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